From
Termini Station
take Metro line "B" ...and follow as below! [approximately 13 minutes]
From "Intercontinental Airport: FCO" or Rome Airport Leonardo Da Vinci
take the first available train to
"Ostiense" station (This is the same direction to "Termini" station). Enter "Ostiense" station and take the "Metro line: "B" (heading towards Laurentina) the 2nd stop is Basilica San Paolo, get out here - notice - on 'via G. Gozzi' side, now that you're out the metro, take a left and turn right soon on viale 'G. Imperatore', pass through via 'G. Chiabrera' and turn right at viale Leonardo da Vinci. . You'll find TwinCities hostel Rome on the left at #223. [approximately 40 minutes]
From
Ciampino International Airport take
bus Terravision all the way to Termini station and then follow as above! [approximately 1 hour]
Remember that from Termini Station you can easily find any of
Rome hostels and never get lost.